International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT)
The mission of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) research group is to decrease significantly the illness and death associated with HIV disease in pregnant women, children, and adolescents worldwide by:
• developing and evaluating safe and cost effective approaches for the interruption of mother to child transmission;
• evaluating treatments for HIV-infected children, adolescents, and pregnant women, including treatment and prevention of co-infections and co-morbidities; and evaluating vaccines for the prevention of HIV sexual transmission among adolescents.
Also, IMPACCT is a site for the Pediatric HIV/AIDS Cohort Study PHACS. PHACS expands observational studies of HIV-infected children and HIV-negative children through two studies. The Adolescent Master Protocol will analyze the effects of perinatally acquired HIV infection on sexual maturation, pubertal development, and cognitive, academic, vocational, and social functioning in pre-adolescents and adolescents in the United States. The Surveillance of Maternal Antiretroviral Therapy Study will analyze information on the 45 long-term safety of fetal and infant exposure to prophylactic antiretroviral chemotherapy.
Website: pactg.s-3.com
Contact: Anita Darcey at (619) 543 – 8080